Cleanup my pathetic prose.
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doc/README
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doc/README
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@ -16,8 +16,8 @@ Because many tools to analyze next-generation sequencing data access
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the data in a very similar way, the GATK can provide a small but
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nearly comprehensive set of traversal types that satisfying the data
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access needs of the majority of analysis tools. For example,
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traversals -Y´by each sequencer read¡ and ´by every read covering
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each locus in a genome¡ are common throughout many tools such as
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traversals "by each sequencer read" and "by every read covering
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each locus in a genome" are common throughout many tools such as
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counting reads, building base quality histograms, reporting average
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coverage of the genome, and calling SNPs. The small number of these
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traversals, shared among many tools enables the core GATK development
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@ -52,28 +52,27 @@ intervals on the genome (ByWindow traversal).
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Dependencies
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------------
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The GATK relies on a Java 6-compatible JRE. At the time of this writing,
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the GATK team tests with Sun JRE version 1.6.0_12-b04.
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the GATK team tests with Sun JRE version 1.6.0_12-b04. Additionally, the
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GATK requires as inputs a sorted, indexed BAM file containing aligned reads
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and a fasta-format reference with associated dictionary file (.dict)and
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index (.fasta.fai).
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Additionally, a sorted, indexed BAM file containing aligned reads and a
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fasta-format reference with associated dictionary file (.dict) and
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index (.fasta.fai) are required inputs to the tool.
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Instructions for preparing input files are available at the site below:
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Instructions for preparing input files are available here:
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http://www.broadinstitute.org/gsa/wiki/index.php/Preparing_input_files
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An example BAM and fasta are provided in the 'resources' directory of
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the GATK.
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The bundled 'resources' directory contains an example BAM and fasta.
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Getting Started
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---------------
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The GATK is distributed with a few standard analyses, including PrintReads,
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Pileup, and DepthOfCoverage. More information on the included walkers is
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available on the following wiki page:
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available here:
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http://www.broadinstitute.org/gsa/wiki/index.php/Built-in_walkers
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To run PrintReads on the included sample data, run the following command:
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To print the reads of the included sample data, untar the package into
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the GenomeAnalysisTK directory and run the following command:
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java -jar GenomeAnalysisTK/GenomeAnalysisTK.jar \
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-T PrintReads \
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@ -82,7 +81,6 @@ java -jar GenomeAnalysisTK/GenomeAnalysisTK.jar \
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Support
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-------
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Documentation for the GATK is available at
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http://www.broadinstitute.org/gsa/wiki. For help using or developing
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for the GATK, bug reports, or feature requests, please email
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gsadevelopers@broadinstitute.org.
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Documentation for the GATK is available at http://www.broadinstitute.org/gsa/wiki.
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For help using the GATK, developing analyses with the GATK, bug reports,
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or feature requests, please email gsadevelopers@broadinstitute.org.
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