gatk-3.8/java/src/org/broadinstitute/sting/utils/analysis/AminoAcidTable.java

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package org.broadinstitute.sting.utils.analysis;
import java.util.HashMap;
/*
* Copyright (c) 2010 The Broad Institute
*
* Permission is hereby granted, free of charge, to any person
* obtaining a copy of this software and associated documentation
* files (the "Software"), to deal in the Software without
* restriction, including without limitation the rights to use,
* copy, modify, merge, publish, distribute, sublicense, and/or sell
* copies of the Software, and to permit persons to whom the
* Software is furnished to do so, subject to the following
* conditions:
*
* The above copyright notice and this permission notice shall be
* included in all copies or substantial portions of the Software.
*
* THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
* EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES
* OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
* NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT
* HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY,
* WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
* FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR
* OTHER DEALINGS IN THE SOFTWARE.
*/
/**
* @author chartl
* @since June 28, 2010
*/
public class AminoAcidTable {
public HashMap<String,AminoAcid> tableByCodon = new HashMap<String,AminoAcid>(21);
public HashMap<String,AminoAcid> tableByCode = new HashMap<String,AminoAcid>(21);
public AminoAcidTable() {
for ( AminoAcid acid : AminoAcid.values() ) {
tableByCode.put(acid.getCode(),acid);
for ( String codon : acid.codons ) {
tableByCodon.put(codon,acid);
}
}
}
// todo -- these functions are for the genomic annotator and are named too generally -- they are
// todo -- actually accessors by codon; thus should be more specific.
public AminoAcid getEukaryoticAA(String codon) {
return tableByCodon.get(codon.toUpperCase());
}
public AminoAcid getMitochondrialAA(String codon, boolean isFirst) {
String upperCodon = codon.toUpperCase();
if ( isFirst && upperCodon.equals("ATT") || upperCodon.equals("ATA") ) {
return AminoAcid.Methionine;
} else if ( upperCodon.equals("AGA") || upperCodon.equals("AGG") ) {
return AminoAcid.Stop_codon;
} else if ( upperCodon.equals("TGA") ) {
return AminoAcid.Tryptophan;
} else {
return tableByCodon.get(upperCodon);
}
}
public AminoAcid getAminoAcidByCode(String code) {
return tableByCode.get(code);
}
}