Heng Li
6c665189ad
r359: identical output to 0.7.2 (without -a)
2013-03-11 23:16:18 -04:00
Heng Li
26f4c704ed
drop the old SAM writer
2013-03-11 22:24:54 -04:00
Heng Li
0b0455ca51
replace PE; BUGGY right now!!
2013-03-11 22:18:23 -04:00
Heng Li
2d01a297fb
Improving 'properly paired' flag.
...
If one end has a low quality tail that happens to have a score-20 hit,
the pair won't be flagged as properly paired because bwa-mem thought it has
multiple hits. By filtering with -T, we won't have this problem.
2013-03-09 18:05:50 -05:00
Heng Li
274c0ac96c
r343: bugfix in mem - wrong mate info for unmap
...
SAM generation is always among the nastiest bits. I would need to refactor at
some point (hardly happening).
2013-03-08 12:40:31 -05:00
Heng Li
b5b50ac8da
r341: bugfix - wrong mate position
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when one end is mapped with a score less than -T. Caused by the -T option.
2013-03-07 21:35:57 -05:00
Heng Li
e70c7c2a71
r284: amend cross-reference hit
...
I really hate this: complex and twisted logic for a nasty scenario that almost
never happens to short reads - but it may become serious when the reference
genome consists of many contigs.
On toy examples, the code seems to work. Don't know if it really works...
2013-02-26 00:03:49 -05:00
Heng Li
20aa848b3c
r279: for PE mapq, consider the number of pairs
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If there are a lot of proper pairs, it is more likely that the best pair is
wrong.
2013-02-25 13:00:35 -05:00
Heng Li
9957e04590
r278: don't perform too many mate-sw
2013-02-25 11:56:02 -05:00
Heng Li
ee59a13109
simplified bwamem.h
...
Hide mem_seed_t and mem_chain_t. Don't expose unnecessary routines.
2013-02-24 12:17:29 -05:00
Heng Li
b4c38bcc1c
append fasta/q comment
2013-02-23 16:57:34 -05:00
Heng Li
17c123d65a
pring paired-end SAM
2013-02-22 16:38:48 -05:00
Heng Li
ba15b787cb
rework PE mapq; don't know if better
2013-02-22 14:47:57 -05:00
Heng Li
6c1a113753
mate-SW for all high-scoring hits
2013-02-22 13:26:23 -05:00
Heng Li
38fc5c8822
reduce mapQ when a read is moved
2013-02-22 12:54:42 -05:00
Heng Li
6a16edc15e
tuning PE mapQ
2013-02-22 12:47:26 -05:00
Heng Li
c0093264de
wrong logic: paired mapQ should <q_pe
2013-02-22 12:34:46 -05:00
Heng Li
c5ce72f593
scoring pairs by score, not by errors
...
This is important for bwa-mem which does local alignment. A short exact match
is worse than a long inexact match. Also fixed a bug in approximating mapping
quality.
2013-02-22 12:10:20 -05:00
Heng Li
ed08d08f36
fixed bugs caused by interger overflow
2013-02-22 11:17:31 -05:00
Heng Li
dfc63acc11
bugfix: another ">" vs. "<" bug
...
That hurts, as I am going to reverse all these again!
2013-02-22 11:06:36 -05:00
Heng Li
d5820177c6
bugfix: wrong mate-sw qry coor for rev
2013-02-22 11:02:14 -05:00
Heng Li
81fe6f8e38
bugfix: a typo leading to wrong pairing
2013-02-22 10:57:07 -05:00
Heng Li
58e4cc207f
bugfix: 1) fill seedcov; 2) pairing not working
2013-02-21 21:26:01 -05:00
Heng Li
a9cae8c9af
minor changes
2013-02-21 10:39:17 -05:00
Heng Li
41624fb347
bugfix: choosing the worse instead of the best
2013-02-20 20:43:22 -05:00
Heng Li
ea8f4f4d34
clean bill from valgrind
2013-02-20 20:26:57 -05:00
Heng Li
5626fe29b7
Well, at least output sth
2013-02-20 19:11:44 -05:00
Heng Li
688872fb1b
code backup
2013-02-19 00:50:39 -05:00
Heng Li
66585b7982
code backup
2013-02-18 16:33:06 -05:00
Heng Li
f0a6285aba
perform mate-SW for some suboptimal alignments
2013-02-16 11:52:04 -05:00
Heng Li
ea9fc7df48
keep the number of SW performed
2013-02-16 11:03:27 -05:00
Heng Li
8ee464478a
matesw working; for testing only
2013-02-16 10:48:50 -05:00
Heng Li
fe2236f6fe
code backup
2013-02-16 10:09:30 -05:00
Heng Li
5f8c6efbc3
forbid x-bounary bns_get_seq(); code backup
2013-02-16 09:48:44 -05:00
Heng Li
df1ff2b36e
better and proper way to infer orinentation
2013-02-14 12:59:32 -05:00
Heng Li
688b524cdf
code backup; tired..
2013-02-13 23:55:56 -05:00
Heng Li
87d619a21f
minor code simplification
2013-02-13 23:16:16 -05:00
Heng Li
604e3d8da1
code backup; to upgrade ksw.{c,h}
2013-02-12 16:15:26 -05:00
Heng Li
2fc469d0c9
code backup
2013-02-12 12:09:36 -05:00
Heng Li
e5ab59db53
Multiple changes:
...
1. Removed bwa.{h,c}. I am not going to finish them anyway.
2. Updated to the latest khash.h, which should be faster.
3. Define 64-bit vector and 128-bit integer/vector in utils.h.
2013-02-12 09:50:28 -05:00
Heng Li
13288e2dcd
code backup
2013-02-12 09:22:47 -05:00
Heng Li
dcb190069a
PE NOT working, yet
2013-02-11 16:10:14 -05:00
Heng Li
99907c98fb
separated and improved SAM printing code
...
This is for the PE mode. The routines may also be useful for bwa-sw, but
probably I won't change the old code.
2013-02-11 15:29:03 -05:00
Heng Li
b6006cbe9d
skip orientations that are much smaller than best
2013-02-11 13:44:39 -05:00
Heng Li
4431e359e2
analyze isize distribution
2013-02-11 12:15:12 -05:00
Heng Li
59eaf650ac
code backup
2013-02-11 10:59:38 -05:00