Commit Graph

113 Commits (ca61fe3ad5a9d4b7d2acf2a780e637b28f056fce)

Author SHA1 Message Date
Heng Li 35ac99b4f7 r815: optionally output ref fasta header
Also fixed a bug in reading .ann files
2014-08-29 10:51:23 -04:00
Heng Li b5cba257c1 r809: new strategy for the -a mode 2014-08-25 11:59:27 -04:00
Heng Li 08517ac09b r764: changed -c in "-x pacbio" to 500 2014-05-13 12:53:24 -04:00
Heng Li a35a6c2580 updated maual page 2014-05-12 12:52:16 -04:00
Heng Li 39a6cd5bb0 r762: cleanup for the new release; unfinished
It will take to make the documentation ready.
2014-05-11 15:15:44 -04:00
Heng Li 6ac8dd5840 r754: added command msg for -h 2014-05-06 16:15:14 -04:00
Heng Li ce3c198245 r749: max_hits tunable on CMD; default to 5 2014-05-04 10:17:03 -04:00
Heng Li 11698fc4e5 r735: fixed a bug caused by merge 2014-04-30 13:12:43 -04:00
Heng Li 76bb49e01b r729: halved band width; doubled patch band width 2014-04-24 16:06:01 -04:00
Heng Li b92bbb47e5 Merge branch '0.7.7-softclip' into layout
Conflicts:
	Makefile
	bwamem.h
	fastmap.c
	main.c
2014-04-24 12:24:49 -04:00
Heng Li 8c12ec4a4b r725: optionally disable hard clipping
as is reqested by the cancer group
2014-04-24 11:56:43 -04:00
Heng Li 00a07f61bf r721: merge overlapping hits by default 2014-04-15 16:16:04 -04:00
Heng Li 4e22270eba r718: merge alnregs overlapping on both query/ref 2014-04-14 17:01:17 -04:00
Heng Li 6d4a6debdc r716: changed -x pbread 2014-04-14 16:04:29 -04:00
Heng Li bbcabfe342 r707: change params for pacbio-to-pacbio 2014-04-10 21:53:52 -04:00
Heng Li db58392e9b dev-469: fixed wrong command line prompt 2014-04-09 13:20:04 -04:00
Heng Li d766591c1e dev-468: fixed a segfault caused by NULL 2014-04-08 22:11:36 -04:00
Heng Li 99f6f9a0d1 dev-467: limit the max #chains to extend 2014-04-08 21:45:49 -04:00
Heng Li f12dfae772 dev-465: a new output format for read overlap
Also moved a few functions to bwamem_extra.c. File bwamem.c is becoming far too
long.
2014-04-08 16:29:36 -04:00
Heng Li b45aeb87e1 dev-464: preset for pacbio read2read aln 2014-04-08 11:40:54 -04:00
Heng Li 172ba83241 dev-463: added option -x to change multiple params
I hate to copy-paste long command line options.
2014-04-07 11:29:36 -04:00
Heng Li 114901b005 dev-r462: refined setting for PacBio; weight flt
The recommended setting in the last commit is wrong. If we can extend a random
seed hit to the full length, we will force the read aligned through break
points, which is wrong. The new setting is better but it may lead to a small
fraction of fragmented alignments.

In addition, I added a filter on the minimum chain weight and tied
min_HSP_score to this filter. It doubles the mapping speed.
2014-04-04 17:01:04 -04:00
Heng Li 41f720dfa7 dev-461: added a heuristic for PacBio data
See the comment above mem_test_chain_sw() for details.
2014-04-04 16:05:41 -04:00
Heng Li b3225581be dev-458: simplified the smem iterator
simpler but less powful.
2014-04-03 15:23:48 -04:00
Heng Li 3efb7c0e91 r455: release bwa-0.7.8 2014-03-31 15:27:23 -04:00
Heng Li 127c00cc96 dev-454: wording change in command line prompt 2014-03-31 12:03:27 -04:00
Heng Li b27bdf1ae0 dev-453: change of -A scales -TdBOELU
These paramemters are all proportional to -A.
2014-03-31 11:52:52 -04:00
Heng Li b7076d9023 dev-r452: allow to specify insert size at cmd
This is also very useful for debugging.
2014-03-31 11:21:03 -04:00
Heng Li 9ce50a4e5e dev-450: support diff ins/del penalties. NO TEST!! 2014-03-28 14:54:06 -04:00
Heng Li 2e9463ebf1 dev-r442: suppress exact full-length matches 2014-02-26 22:04:19 -05:00
Heng Li ce026a07fc r439: expose mem_opt_t::max_matesw 2014-02-19 13:10:33 -05:00
Heng Li 10cb6b0507 r428: allow to change the default chain_drop_ratio 2013-12-30 16:18:45 -05:00
Heng Li 4219e58623 r423: bugfix - SE hits not random 2013-11-23 09:36:26 -05:00
Heng Li c564653b40 r416: removed a line of debugging code 2013-09-12 10:41:43 -04:00
Heng Li 623da055e1 alternative way to estimate mapQ
the old mapQ estimate is too conservative
2013-09-06 12:31:47 -04:00
Heng Li ed78df9184 Merge branch 'master' into clip2 2013-08-28 16:00:34 -04:00
Heng Li 3b84c03c1e r406: allow to use diff clipping penalties
for 5'-end or for 3'-end
2013-08-28 15:59:05 -04:00
John Marshall 128ffc089b Complain when bwa mem is given too many filenames
Reads in extra .fq filenames beyond "bwa mem index one.fq two.fq"
will not be aligned, so complain about such invalid usage instead.
2013-06-14 14:00:24 +01:00
Heng Li 9735d7a31a conform to the latest (unpublished) SAM spec
for chimeric alignments
2013-05-22 19:45:16 -04:00
Rob Davies 0aa7e0a402 Ensure exit status of 1 if given invalid options or index files are not found.
Added missing default cases in option scanning.
Ensure exit value is 1 if bwa_idx_load or bwa_idx_infer_prefix fail.
These changes extend the previous one, which only fixed the mem aligner.
2013-04-29 13:58:28 +01:00
Rob Davies e88529687f Merge branch 'master' into master_fixes. Merged up to r389.
Conflicts:
	bwamem.c
	kopen.c
2013-04-29 12:09:30 +01:00
Heng Li 1a2bd2cf91 r389: return non-zero upon errors 2013-04-27 10:08:01 -04:00
Heng Li 19cb7cd7ed r388: cleanup mem_process_seqs() interface
Print output outside the function and allow to feed insert size distribution.
2013-04-26 12:31:18 -04:00
Rob Davies 90ecd344ba Merge branch 'master' into master_fixes. Merged up to master r375.
Conflicts:
	bwt.c
2013-04-11 11:15:39 +01:00
Heng Li 53bb846407 r373: optionally distable mate rescue 2013-04-09 16:13:55 -04:00
Rob Davies aabd990e8f Merge branch 'master' into master_fixes
Conflicts:
	Makefile
	bwape.c
	bwase.c
	bwtsw2_aux.c
	stdaln.c
2013-03-08 16:46:45 +00:00
Heng Li b0a76884e8 r340: feature freeze; updated the manpage
I will stop adding new features to bwa and prepare for the next release. I will
briefly evaluate the variant calling accuracy before the release.
2013-03-07 11:51:23 -05:00
Heng Li 3e3236dfc4 r337: mem - always read even number of reads
In the old code, we may read odd number of reads from an interleaved fastq.
2013-03-07 11:00:15 -05:00
Heng Li 5fbd454682 r332: added output threshold
Otherwise there are far too many short hits
2013-03-05 22:49:38 -05:00
Heng Li 07921659cf move mem_fill_scmat() to bwa.{h,c} 2013-03-05 09:38:12 -05:00