Heng Li
c5ce72f593
scoring pairs by score, not by errors
...
This is important for bwa-mem which does local alignment. A short exact match
is worse than a long inexact match. Also fixed a bug in approximating mapping
quality.
2013-02-22 12:10:20 -05:00
Heng Li
ed08d08f36
fixed bugs caused by interger overflow
2013-02-22 11:17:31 -05:00
Heng Li
dfc63acc11
bugfix: another ">" vs. "<" bug
...
That hurts, as I am going to reverse all these again!
2013-02-22 11:06:36 -05:00
Heng Li
d5820177c6
bugfix: wrong mate-sw qry coor for rev
2013-02-22 11:02:14 -05:00
Heng Li
81fe6f8e38
bugfix: a typo leading to wrong pairing
2013-02-22 10:57:07 -05:00
Heng Li
58e4cc207f
bugfix: 1) fill seedcov; 2) pairing not working
2013-02-21 21:26:01 -05:00
Heng Li
d4cf6d97a6
bugfix: memory leak
2013-02-21 15:04:31 -05:00
Heng Li
a578688fa8
generate multiple alignments from one chain
2013-02-21 14:58:51 -05:00
Heng Li
cfbc4c89e3
perform extension when there are, say, 20bp tandem
2013-02-21 14:34:10 -05:00
Heng Li
54da54ffd4
extend more seeds (and thus slower...)
2013-02-21 12:52:00 -05:00
Heng Li
f8829318cf
weakened the chain filter
2013-02-21 12:25:20 -05:00
Heng Li
84a328764a
bugfix: mis-chaining caused by integer overflow
...
I really need to rewrite kbtree some time.
2013-02-21 11:42:30 -05:00
Heng Li
a9cae8c9af
minor changes
2013-02-21 10:39:17 -05:00
Heng Li
41624fb347
bugfix: choosing the worse instead of the best
2013-02-20 20:43:22 -05:00
Heng Li
ea8f4f4d34
clean bill from valgrind
2013-02-20 20:26:57 -05:00
Heng Li
5626fe29b7
Well, at least output sth
2013-02-20 19:11:44 -05:00
Heng Li
a7d574d125
backup comments
2013-02-20 01:11:38 -05:00
Heng Li
688872fb1b
code backup
2013-02-19 00:50:39 -05:00
Heng Li
66585b7982
code backup
2013-02-18 16:33:06 -05:00
Heng Li
f0a6285aba
perform mate-SW for some suboptimal alignments
2013-02-16 11:52:04 -05:00
Heng Li
ea9fc7df48
keep the number of SW performed
2013-02-16 11:03:27 -05:00
Heng Li
8ee464478a
matesw working; for testing only
2013-02-16 10:48:50 -05:00
Heng Li
fe2236f6fe
code backup
2013-02-16 10:09:30 -05:00
Heng Li
5f8c6efbc3
forbid x-bounary bns_get_seq(); code backup
2013-02-16 09:48:44 -05:00
Heng Li
df1ff2b36e
better and proper way to infer orinentation
2013-02-14 12:59:32 -05:00
Heng Li
688b524cdf
code backup; tired..
2013-02-13 23:55:56 -05:00
Heng Li
87d619a21f
minor code simplification
2013-02-13 23:16:16 -05:00
Heng Li
557daabf38
bugfix: bug in the new ksw.c
...
On my test data, one alignment is different, caused by polyA
2013-02-12 17:48:46 -05:00
Heng Li
28a7d501f2
updated to the latest ksw; NOT TESTED YET!!!
2013-02-12 16:35:05 -05:00
Heng Li
604e3d8da1
code backup; to upgrade ksw.{c,h}
2013-02-12 16:15:26 -05:00
Heng Li
325ba8213b
move mark primary to worker1()
2013-02-12 15:54:55 -05:00
Heng Li
cd0969332f
keep track of the "parent" of a secondary
2013-02-12 15:52:23 -05:00
Heng Li
22b79b3475
mark primary, instead of dropping secondary
2013-02-12 15:34:44 -05:00
Heng Li
2fc469d0c9
code backup
2013-02-12 12:09:36 -05:00
Heng Li
cfdc938fc3
to exclude "test64"
2013-02-12 10:39:16 -05:00
Heng Li
95d18449b3
merge bseq.{h,c} to utils.{h,c}
...
I do not like many small files.
2013-02-12 10:36:15 -05:00
Heng Li
6ad5a3c086
removed color-space support
...
which has been broken since 0.6.x
2013-02-12 10:21:17 -05:00
Heng Li
e5ab59db53
Multiple changes:
...
1. Removed bwa.{h,c}. I am not going to finish them anyway.
2. Updated to the latest khash.h, which should be faster.
3. Define 64-bit vector and 128-bit integer/vector in utils.h.
2013-02-12 09:50:28 -05:00
Heng Li
13288e2dcd
code backup
2013-02-12 09:22:47 -05:00
Heng Li
dcb190069a
PE NOT working, yet
2013-02-11 16:10:14 -05:00
Heng Li
99907c98fb
separated and improved SAM printing code
...
This is for the PE mode. The routines may also be useful for bwa-sw, but
probably I won't change the old code.
2013-02-11 15:29:03 -05:00
Heng Li
b6006cbe9d
skip orientations that are much smaller than best
2013-02-11 13:44:39 -05:00
Heng Li
4431e359e2
analyze isize distribution
2013-02-11 12:15:12 -05:00
Heng Li
987d4b4205
fixed a stupid bug in fastq reading
2013-02-11 11:27:35 -05:00
Heng Li
59eaf650ac
code backup
2013-02-11 10:59:38 -05:00
Heng Li
f4c0672800
move sort_and_dedup() to worker1()
2013-02-10 12:55:19 -05:00
Heng Li
c310fb7424
a little refactoring for PE support
2013-02-10 12:24:33 -05:00
Heng Li
cb55617f50
added a new line
2013-02-08 22:12:18 -05:00
Heng Li
95a79afe71
command-line prompt
2013-02-08 22:11:44 -05:00
Heng Li
829664d6b5
missing identical hits; improved sub_n
2013-02-08 17:55:35 -05:00