Heng Li
80e4ecfa79
r998: smart pairing; allow mixture of SE/PE reads
2014-11-18 14:30:22 -05:00
Heng Li
9bf898fa10
r963: expose mask_level
2014-10-30 11:33:43 -04:00
Heng Li
76a15ea91b
r933: with bwa-postalt ready, drop option -g
2014-10-21 00:23:14 -04:00
Heng Li
a6b5a30dab
r930: use 3rd round seeding by default
...
This strategy is similar to the seeding heuristic used by LAST. When it is used
alone, it is not as accurate as the current seeding strategy at least for short
reads. However, it may do a better job for a long contig mapped to multiple ALT
contigs. This seeding strategy is also relatively cheap to perform.
2014-10-20 17:34:15 -04:00
Heng Li
bfd5e1840f
shm works on small files, but not large ones
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I don't know why. SHMMAX, SHMALL and SHMMNI are large enough.
2014-10-15 15:44:06 -04:00
Heng Li
0a2cf98293
r876: optionally ignore idxbase.alt file
2014-09-27 23:21:50 -04:00
Heng Li
9af36064e8
r867: fixed a few bugs; added ALT hits to XA
2014-09-19 16:50:21 -04:00
Heng Li
c982443210
r854: improved the calculation of pa
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and build pa filtering into BWA-MEM
2014-09-17 16:26:28 -04:00
Heng Li
92bc6849a3
r844: added intra-species contig mapping mode
2014-09-16 10:53:07 -04:00
Heng Li
90518f11e3
r843: presetting for ONT 2d reads
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Somewhat working for 1d reads, but not very well
2014-09-16 10:38:15 -04:00
Heng Li
4b6eeb34c8
r830: optionally fixed chunk size
2014-09-15 23:42:24 -04:00
Heng Li
5d26ab0ee3
r828: changed the default scoring for pacbio
2014-09-15 23:22:05 -04:00
Heng Li
35ac99b4f7
r815: optionally output ref fasta header
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Also fixed a bug in reading .ann files
2014-08-29 10:51:23 -04:00
Heng Li
b5cba257c1
r809: new strategy for the -a mode
2014-08-25 11:59:27 -04:00
Heng Li
08517ac09b
r764: changed -c in "-x pacbio" to 500
2014-05-13 12:53:24 -04:00
Heng Li
a35a6c2580
updated maual page
2014-05-12 12:52:16 -04:00
Heng Li
39a6cd5bb0
r762: cleanup for the new release; unfinished
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It will take to make the documentation ready.
2014-05-11 15:15:44 -04:00
Heng Li
6ac8dd5840
r754: added command msg for -h
2014-05-06 16:15:14 -04:00
Heng Li
ce3c198245
r749: max_hits tunable on CMD; default to 5
2014-05-04 10:17:03 -04:00
Heng Li
11698fc4e5
r735: fixed a bug caused by merge
2014-04-30 13:12:43 -04:00
Heng Li
76bb49e01b
r729: halved band width; doubled patch band width
2014-04-24 16:06:01 -04:00
Heng Li
b92bbb47e5
Merge branch '0.7.7-softclip' into layout
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Conflicts:
Makefile
bwamem.h
fastmap.c
main.c
2014-04-24 12:24:49 -04:00
Heng Li
8c12ec4a4b
r725: optionally disable hard clipping
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as is reqested by the cancer group
2014-04-24 11:56:43 -04:00
Heng Li
00a07f61bf
r721: merge overlapping hits by default
2014-04-15 16:16:04 -04:00
Heng Li
4e22270eba
r718: merge alnregs overlapping on both query/ref
2014-04-14 17:01:17 -04:00
Heng Li
6d4a6debdc
r716: changed -x pbread
2014-04-14 16:04:29 -04:00
Heng Li
bbcabfe342
r707: change params for pacbio-to-pacbio
2014-04-10 21:53:52 -04:00
Heng Li
db58392e9b
dev-469: fixed wrong command line prompt
2014-04-09 13:20:04 -04:00
Heng Li
d766591c1e
dev-468: fixed a segfault caused by NULL
2014-04-08 22:11:36 -04:00
Heng Li
99f6f9a0d1
dev-467: limit the max #chains to extend
2014-04-08 21:45:49 -04:00
Heng Li
f12dfae772
dev-465: a new output format for read overlap
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Also moved a few functions to bwamem_extra.c. File bwamem.c is becoming far too
long.
2014-04-08 16:29:36 -04:00
Heng Li
b45aeb87e1
dev-464: preset for pacbio read2read aln
2014-04-08 11:40:54 -04:00
Heng Li
172ba83241
dev-463: added option -x to change multiple params
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I hate to copy-paste long command line options.
2014-04-07 11:29:36 -04:00
Heng Li
114901b005
dev-r462: refined setting for PacBio; weight flt
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The recommended setting in the last commit is wrong. If we can extend a random
seed hit to the full length, we will force the read aligned through break
points, which is wrong. The new setting is better but it may lead to a small
fraction of fragmented alignments.
In addition, I added a filter on the minimum chain weight and tied
min_HSP_score to this filter. It doubles the mapping speed.
2014-04-04 17:01:04 -04:00
Heng Li
41f720dfa7
dev-461: added a heuristic for PacBio data
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See the comment above mem_test_chain_sw() for details.
2014-04-04 16:05:41 -04:00
Heng Li
b3225581be
dev-458: simplified the smem iterator
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simpler but less powful.
2014-04-03 15:23:48 -04:00
Heng Li
3efb7c0e91
r455: release bwa-0.7.8
2014-03-31 15:27:23 -04:00
Heng Li
127c00cc96
dev-454: wording change in command line prompt
2014-03-31 12:03:27 -04:00
Heng Li
b27bdf1ae0
dev-453: change of -A scales -TdBOELU
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These paramemters are all proportional to -A.
2014-03-31 11:52:52 -04:00
Heng Li
b7076d9023
dev-r452: allow to specify insert size at cmd
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This is also very useful for debugging.
2014-03-31 11:21:03 -04:00
Heng Li
9ce50a4e5e
dev-450: support diff ins/del penalties. NO TEST!!
2014-03-28 14:54:06 -04:00
Heng Li
2e9463ebf1
dev-r442: suppress exact full-length matches
2014-02-26 22:04:19 -05:00
Heng Li
ce026a07fc
r439: expose mem_opt_t::max_matesw
2014-02-19 13:10:33 -05:00
Heng Li
10cb6b0507
r428: allow to change the default chain_drop_ratio
2013-12-30 16:18:45 -05:00
Heng Li
4219e58623
r423: bugfix - SE hits not random
2013-11-23 09:36:26 -05:00
Heng Li
c564653b40
r416: removed a line of debugging code
2013-09-12 10:41:43 -04:00
Heng Li
623da055e1
alternative way to estimate mapQ
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the old mapQ estimate is too conservative
2013-09-06 12:31:47 -04:00
Heng Li
ed78df9184
Merge branch 'master' into clip2
2013-08-28 16:00:34 -04:00
Heng Li
3b84c03c1e
r406: allow to use diff clipping penalties
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for 5'-end or for 3'-end
2013-08-28 15:59:05 -04:00
John Marshall
128ffc089b
Complain when bwa mem is given too many filenames
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Reads in extra .fq filenames beyond "bwa mem index one.fq two.fq"
will not be aligned, so complain about such invalid usage instead.
2013-06-14 14:00:24 +01:00