5e00d08346
r939: fixed a memory leak (issue #35 )
2014-10-21 09:26:19 -04:00
76a15ea91b
r933: with bwa-postalt ready, drop option -g
2014-10-21 00:23:14 -04:00
a6b5a30dab
r930: use 3rd round seeding by default
...
This strategy is similar to the seeding heuristic used by LAST. When it is used
alone, it is not as accurate as the current seeding strategy at least for short
reads. However, it may do a better job for a long contig mapped to multiple ALT
contigs. This seeding strategy is also relatively cheap to perform.
2014-10-20 17:34:15 -04:00
038af2a551
r929: added simplified LAST-like seeding
2014-10-20 17:00:31 -04:00
3370ae9e35
r926: prepare to move -g to bwa-postalt.js
2014-10-19 20:43:53 -04:00
a06646493b
r915: fixed broken example.c
2014-10-17 16:17:28 -04:00
8af17b3478
r912: very minor improvement
2014-10-17 12:14:18 -04:00
c280274331
r911: check before attempting adding
2014-10-17 12:13:09 -04:00
76a365a95f
r907: revert to -g.8 by default
2014-10-16 15:56:33 -04:00
d8d8b230d1
r906: don't reduce non-ALT mapQ by default
2014-10-16 15:15:23 -04:00
e318d8e7e5
r905: lower peak RAM for "shm -f"
2014-10-16 11:22:09 -04:00
ad0da1418f
r904: optionally create tmp files for shm staging
2014-10-16 10:52:59 -04:00
97a3102c89
r903: updated revision number
2014-10-16 10:26:25 -04:00
6a0952948d
shared memory
2014-10-15 14:44:08 -04:00
c5e859b49f
r898: read the index into a single memory block
...
Prepare for shared memory. Not used now.
2014-10-15 12:27:45 -04:00
71277f0fea
r896: more flexible ALT reading
2014-10-14 23:37:24 -04:00
2a18fa114f
r895: increase the default max_XA_hits_alt to 200
...
Because there are >100 HLA haplotypes
2014-10-14 16:58:42 -04:00
df20911110
r890: bns_intv2rid() may wrongly return -1
2014-10-14 14:49:53 -04:00
7b62fbb4ba
r880: bug in writing .ann file
2014-10-02 15:34:49 -04:00
a03d01f944
r878: XA is given to the best alignment
...
Non-ALT hits may get ALT hits in the XA tag. This will simplify haplotype
assignment.
2014-09-30 13:50:51 -04:00
0a2cf98293
r876: optionally ignore idxbase.alt file
2014-09-27 23:21:50 -04:00
dae4ca3ced
r875: invalid SAM output for ALT hits
2014-09-26 15:29:08 -04:00
7426a750ec
r868: use soft clip for ALT hits
2014-09-19 16:58:18 -04:00
9af36064e8
r867: fixed a few bugs; added ALT hits to XA
2014-09-19 16:50:21 -04:00
a41afe4c97
These files were committed on a wrong branch
2014-09-18 10:49:35 -04:00
a32d44d8d6
r855: show ALT hits in the PE mode, too
...
In the previous version, it does not
2014-09-17 23:07:56 -04:00
c982443210
r854: improved the calculation of pa
...
and build pa filtering into BWA-MEM
2014-09-17 16:26:28 -04:00
825ae92e58
r849: the pa tag now gives a number
...
... which is the ratio of this hit to the best ALT hit.
2014-09-17 13:05:35 -04:00
6f37c14f26
r848: tag alignments with primary ALT
2014-09-16 18:52:49 -04:00
a458442b24
r845: updated NEWS
...
I will use the new version for a while and then release it.
2014-09-16 14:38:41 -04:00
92bc6849a3
r844: added intra-species contig mapping mode
2014-09-16 10:53:07 -04:00
90518f11e3
r843: presetting for ONT 2d reads
...
Somewhat working for 1d reads, but not very well
2014-09-16 10:38:15 -04:00
4b6eeb34c8
r830: optionally fixed chunk size
2014-09-15 23:42:24 -04:00
624687b072
r829: killed a harmless gcc warning
2014-09-15 23:33:22 -04:00
5d26ab0ee3
r828: changed the default scoring for pacbio
2014-09-15 23:22:05 -04:00
b07587f806
r827: an alt hit as good as a pri hit as supp
2014-09-15 16:07:51 -04:00
bd85af08ab
r826: improved alt mapping for PE
2014-09-15 12:13:04 -04:00
aee53f1334
r824: ALT mapping seems working
2014-09-15 00:29:05 -04:00
015ab3f6c3
r823: towards ALT support
2014-09-14 16:41:14 -04:00
8d2b93156b
r821: more relax on containing seeds
2014-09-12 10:35:49 -04:00
f4aedddee6
r819: bugfix - added too many sub-SMEMs
2014-09-08 11:32:48 -04:00
35ac99b4f7
r815: optionally output ref fasta header
...
Also fixed a bug in reading .ann files
2014-08-29 10:51:23 -04:00
1e611b235c
r810: add err_puts()
...
puts() adds '\n', but fputs() does not.
2014-08-26 11:07:24 -04:00
b5cba257c1
r809: new strategy for the -a mode
2014-08-25 11:59:27 -04:00
bf7d1d46ca
r808: a minor bug with the new index -b
2014-08-25 10:36:24 -04:00
1bba5ef20e
r807: allow to change block size in bwt_gen
...
For a very large reference genome, the default is too small.
2014-08-25 10:31:54 -04:00
705aa53894
Released 0.7.10
2014-07-13 22:57:27 -04:00
7fd6a11569
r788: segfault when the last ref is "weird"
...
mem_patch_reg() did not check if two hits are on the same strand, which may
lead to an alignment bridging the forward-backward boundary.
2014-07-10 10:53:56 -04:00
cffff4338f
r787: use mem_seed_sw() also for non-PacBio reads
...
In the previous version, mem_seed_sw() is only used for PacBio reads to filter
bad seeds. For non-PacBio long queries, bwa-mem uses mem_chain2aln_short() for
a similar purpose. However, it turns out that mem_chain2aln_short() is not
effective given long near-tandem repeats. Bwa-mem still wastes a lot of time
of futile ref substring and extensions.
In this commit, mem_chain2aln_short() has been removed. mem_seed_sw() is used
if the query sequence is long enough (~700bp). For shorter reads, the results
should be almost identical to the previous version.
2014-07-10 10:30:22 -04:00
3efc33160c
0.7.9a-r786: fixed a segfault in a rare case
...
More likely to happen given a circular genome
2014-05-19 16:47:25 -04:00
Heng Li