Heng Li
9bf898fa10
r963: expose mask_level
2014-10-30 11:33:43 -04:00
Heng Li
6db2fd98aa
r960: merge changes from the master branch
2014-10-28 13:46:40 -04:00
Heng Li
3d129be642
r943: change the default -y to 20, but ...
...
for GRCh38 ALT, this is not enough. We need -y at least 40 to get high accuracy
because a locus at chr19 has 35 copies.
2014-10-22 12:42:58 -04:00
Heng Li
4177d6c2c7
r942: ignore ALT hits when counting n_sub for ...
...
non-ALT hits. Counting leads to underestimated mapQ.
2014-10-22 10:24:16 -04:00
Heng Li
60b728487a
r941: set a min length for 3rd-round seeding
2014-10-21 13:15:42 -04:00
Heng Li
282130a64e
r940: fixed a bug - missing primary hit
2014-10-21 12:57:49 -04:00
Heng Li
5e00d08346
r939: fixed a memory leak (issue #35 )
2014-10-21 09:26:19 -04:00
Heng Li
76a15ea91b
r933: with bwa-postalt ready, drop option -g
2014-10-21 00:23:14 -04:00
Heng Li
a6b5a30dab
r930: use 3rd round seeding by default
...
This strategy is similar to the seeding heuristic used by LAST. When it is used
alone, it is not as accurate as the current seeding strategy at least for short
reads. However, it may do a better job for a long contig mapped to multiple ALT
contigs. This seeding strategy is also relatively cheap to perform.
2014-10-20 17:34:15 -04:00
Heng Li
038af2a551
r929: added simplified LAST-like seeding
2014-10-20 17:00:31 -04:00
Heng Li
3370ae9e35
r926: prepare to move -g to bwa-postalt.js
2014-10-19 20:43:53 -04:00
Heng Li
a06646493b
r915: fixed broken example.c
2014-10-17 16:17:28 -04:00
Heng Li
8af17b3478
r912: very minor improvement
2014-10-17 12:14:18 -04:00
Heng Li
c280274331
r911: check before attempting adding
2014-10-17 12:13:09 -04:00
Heng Li
76a365a95f
r907: revert to -g.8 by default
2014-10-16 15:56:33 -04:00
Heng Li
d8d8b230d1
r906: don't reduce non-ALT mapQ by default
2014-10-16 15:15:23 -04:00
Heng Li
e318d8e7e5
r905: lower peak RAM for "shm -f"
2014-10-16 11:22:09 -04:00
Heng Li
ad0da1418f
r904: optionally create tmp files for shm staging
2014-10-16 10:52:59 -04:00
Heng Li
97a3102c89
r903: updated revision number
2014-10-16 10:26:25 -04:00
Heng Li
6a0952948d
shared memory
2014-10-15 14:44:08 -04:00
Heng Li
c5e859b49f
r898: read the index into a single memory block
...
Prepare for shared memory. Not used now.
2014-10-15 12:27:45 -04:00
Heng Li
71277f0fea
r896: more flexible ALT reading
2014-10-14 23:37:24 -04:00
Heng Li
2a18fa114f
r895: increase the default max_XA_hits_alt to 200
...
Because there are >100 HLA haplotypes
2014-10-14 16:58:42 -04:00
Heng Li
df20911110
r890: bns_intv2rid() may wrongly return -1
2014-10-14 14:49:53 -04:00
Heng Li
7b62fbb4ba
r880: bug in writing .ann file
2014-10-02 15:34:49 -04:00
Heng Li
a03d01f944
r878: XA is given to the best alignment
...
Non-ALT hits may get ALT hits in the XA tag. This will simplify haplotype
assignment.
2014-09-30 13:50:51 -04:00
Heng Li
0a2cf98293
r876: optionally ignore idxbase.alt file
2014-09-27 23:21:50 -04:00
Heng Li
dae4ca3ced
r875: invalid SAM output for ALT hits
2014-09-26 15:29:08 -04:00
Heng Li
7426a750ec
r868: use soft clip for ALT hits
2014-09-19 16:58:18 -04:00
Heng Li
9af36064e8
r867: fixed a few bugs; added ALT hits to XA
2014-09-19 16:50:21 -04:00
Heng Li
a41afe4c97
These files were committed on a wrong branch
2014-09-18 10:49:35 -04:00
Heng Li
a32d44d8d6
r855: show ALT hits in the PE mode, too
...
In the previous version, it does not
2014-09-17 23:07:56 -04:00
Heng Li
c982443210
r854: improved the calculation of pa
...
and build pa filtering into BWA-MEM
2014-09-17 16:26:28 -04:00
Heng Li
825ae92e58
r849: the pa tag now gives a number
...
... which is the ratio of this hit to the best ALT hit.
2014-09-17 13:05:35 -04:00
Heng Li
6f37c14f26
r848: tag alignments with primary ALT
2014-09-16 18:52:49 -04:00
Heng Li
a458442b24
r845: updated NEWS
...
I will use the new version for a while and then release it.
2014-09-16 14:38:41 -04:00
Heng Li
92bc6849a3
r844: added intra-species contig mapping mode
2014-09-16 10:53:07 -04:00
Heng Li
90518f11e3
r843: presetting for ONT 2d reads
...
Somewhat working for 1d reads, but not very well
2014-09-16 10:38:15 -04:00
Heng Li
4b6eeb34c8
r830: optionally fixed chunk size
2014-09-15 23:42:24 -04:00
Heng Li
624687b072
r829: killed a harmless gcc warning
2014-09-15 23:33:22 -04:00
Heng Li
5d26ab0ee3
r828: changed the default scoring for pacbio
2014-09-15 23:22:05 -04:00
Heng Li
b07587f806
r827: an alt hit as good as a pri hit as supp
2014-09-15 16:07:51 -04:00
Heng Li
bd85af08ab
r826: improved alt mapping for PE
2014-09-15 12:13:04 -04:00
Heng Li
aee53f1334
r824: ALT mapping seems working
2014-09-15 00:29:05 -04:00
Heng Li
015ab3f6c3
r823: towards ALT support
2014-09-14 16:41:14 -04:00
Heng Li
8d2b93156b
r821: more relax on containing seeds
2014-09-12 10:35:49 -04:00
Heng Li
f4aedddee6
r819: bugfix - added too many sub-SMEMs
2014-09-08 11:32:48 -04:00
Heng Li
35ac99b4f7
r815: optionally output ref fasta header
...
Also fixed a bug in reading .ann files
2014-08-29 10:51:23 -04:00
Heng Li
1e611b235c
r810: add err_puts()
...
puts() adds '\n', but fputs() does not.
2014-08-26 11:07:24 -04:00
Heng Li
b5cba257c1
r809: new strategy for the -a mode
2014-08-25 11:59:27 -04:00