Commit Graph

721 Commits (10de1e0b747194ca6b21eaa056df5ef5fb87b4d7)

Author SHA1 Message Date
Heng Li 10de1e0b74 optionally output debegging info 2014-11-05 13:20:33 -05:00
Heng Li 0eee4fa1b0 nothing, really 2014-11-04 16:00:25 -05:00
Heng Li 2a41772d0a more command line help 2014-11-04 15:41:18 -05:00
Heng Li e5d7f4fc30 change the default max_len 2014-11-04 15:31:33 -05:00
Heng Li ccf03ffd22 control min-match-length
we still need this to kill false mapping/alignment
2014-11-04 15:26:10 -05:00
Heng Li de268247db type primary exons first and then the rest 2014-11-04 15:09:21 -05:00
Heng Li 12fff1ad57 a bit code cleanup 2014-11-04 14:30:31 -05:00
Heng Li 96fba0f2f4 proper homozygous typing; fixed a low-level bug 2014-11-04 11:38:05 -05:00
Heng Li ace18171b0 backup 2014-11-04 10:07:14 -05:00
Heng Li 4cbb0cb829 polished the run script 2014-11-03 15:29:02 -05:00
Heng Li 9dbf152e31 added the pipeline script 2014-11-03 15:16:14 -05:00
Heng Li 40c4a6ffe1 better CLI; more comments 2014-11-03 12:09:29 -05:00
Heng Li 4bc01e90c8 not used any more 2014-11-03 11:51:25 -05:00
Heng Li b7d0a2d537 first HLA typing script 2014-11-03 11:47:23 -05:00
Heng Li 9bf898fa10 r963: expose mask_level 2014-10-30 11:33:43 -04:00
Heng Li 6db2fd98aa r960: merge changes from the master branch 2014-10-28 13:46:40 -04:00
Heng Li 0f8a164bd3 bugfix: .ctw not generated properly 2014-10-25 23:08:29 -04:00
Heng Li 2bfcc421d9 bugfix: alignments not outputted 2014-10-25 22:13:31 -04:00
Heng Li 7327f8fa10 output all overlapping HLA hits
A contig longer than HLA genes may not get hits to HLA and thus won't be used
in typing.
2014-10-25 12:00:15 -04:00
Heng Li 33938e1ed0 save reads mapped to each HLA gene
for downstream typing
2014-10-24 16:54:48 -04:00
Heng Li ba3ab0ca98 removed hla typing - not good enough 2014-10-24 14:52:16 -04:00
Heng Li 7a8019e6ee removed debugging code 2014-10-24 14:51:05 -04:00
Heng Li 7c362bef69 added another paper 2014-10-23 15:15:20 -04:00
Heng Li 3a1da27c1c added Bai et al. Seems good, too. 2014-10-23 15:08:18 -04:00
Heng Li d61a1226a8 highlight Liu et al. It seems good. 2014-10-23 14:52:48 -04:00
Heng Li f005ea4bf3 coarse HLA typing and doc 2014-10-23 14:42:45 -04:00
Heng Li 3d129be642 r943: change the default -y to 20, but ...
for GRCh38 ALT, this is not enough. We need -y at least 40 to get high accuracy
because a locus at chr19 has 35 copies.
2014-10-22 12:42:58 -04:00
Heng Li 4177d6c2c7 r942: ignore ALT hits when counting n_sub for ...
non-ALT hits. Counting leads to underestimated mapQ.
2014-10-22 10:24:16 -04:00
Heng Li 60b728487a r941: set a min length for 3rd-round seeding 2014-10-21 13:15:42 -04:00
Heng Li 282130a64e r940: fixed a bug - missing primary hit 2014-10-21 12:57:49 -04:00
Heng Li 5e00d08346 r939: fixed a memory leak (issue #35) 2014-10-21 09:26:19 -04:00
Heng Li 574098d034 updated directory name 2014-10-21 00:57:06 -04:00
Heng Li 4260699a09 updated ALT readme due to recent changes 2014-10-21 00:55:00 -04:00
Heng Li 76a15ea91b r933: with bwa-postalt ready, drop option -g 2014-10-21 00:23:14 -04:00
Heng Li 2bfa3c767b CLI help 2014-10-21 00:22:59 -04:00
Heng Li 497913d404 working largely as expected 2014-10-21 00:16:41 -04:00
Heng Li a6b5a30dab r930: use 3rd round seeding by default
This strategy is similar to the seeding heuristic used by LAST. When it is used
alone, it is not as accurate as the current seeding strategy at least for short
reads. However, it may do a better job for a long contig mapped to multiple ALT
contigs. This seeding strategy is also relatively cheap to perform.
2014-10-20 17:34:15 -04:00
Heng Li 038af2a551 r929: added simplified LAST-like seeding 2014-10-20 17:00:31 -04:00
Heng Li 25d45512d9 code backup 2014-10-20 14:17:56 -04:00
Heng Li 6f41a27e27 towards adding "-r" to postprocessing 2014-10-19 20:53:47 -04:00
Heng Li 3370ae9e35 r926: prepare to move -g to bwa-postalt.js 2014-10-19 20:43:53 -04:00
Heng Li 6e13694721 removed coverity 2014-10-17 21:46:11 -04:00
Heng Li e65dc133f4 updated Travis CI link 2014-10-17 21:34:43 -04:00
Heng Li f968b4b73d added drone build 2014-10-17 21:28:44 -04:00
Heng Li 059c8eb899 for coverity 2014-10-17 21:03:11 -04:00
Heng Li c4ac1bee88 added Travis CI integration 2014-10-17 17:02:26 -04:00
Heng Li 1b2eb4c9ab added travis CI 2014-10-17 16:39:14 -04:00
Heng Li d0a796b644 moved bwashm.o to AOBJS 2014-10-17 16:23:35 -04:00
Heng Li c8ae5029b3 minor change to example 2014-10-17 16:19:21 -04:00
Heng Li a06646493b r915: fixed broken example.c 2014-10-17 16:17:28 -04:00