Commit Graph

1001 Commits (main)

Author SHA1 Message Date
Heng Li 9649f3496f Merge branch 'dev' 2014-12-02 10:35:02 -05:00
Heng Li 393735d7f1 more FAQs on ALT mapping 2014-12-02 10:30:35 -05:00
Heng Li ae4aa77b50 Merge branch 'dev' 2014-12-01 09:51:05 -05:00
Heng Li d6e8e5929b Updated READMEs a little 2014-12-01 09:50:47 -05:00
Heng Li 309d1c543d Merge branch 'dev' 2014-11-26 13:27:21 -05:00
Heng Li 9d8c906e4c r1017: process I/O in a separate thread
Previously, bwa-mem waits for I/O. When the input data comes from a slow source
(I/O or piped from a slow program), bwa-mem may spend significant amount of
wall-clock time in the single-thread mode. The same may also happen when bwa-mem
writes to slow target. This commit uses two sequence buffers. it allows bwa-mem
to map one buffer while filling or dumping the other buffer. When bwa-mem is run
on 16 threads using the bwa.kit pipeline, the wall clock time is reduced by 30%.
2014-11-26 12:32:48 -05:00
Heng Li cb8992459f Merge branch 'dev' 2014-11-19 12:54:30 -05:00
Heng Li 3633436a3d added download link explicitly 2014-11-19 12:54:15 -05:00
Heng Li decc812f77 Merge branch 'dev' 2014-11-19 12:47:20 -05:00
Heng Li 6609bafa17 moved directory structure to this README
There are too many README files...
2014-11-19 12:45:21 -05:00
Heng Li d58beeee56 smarter about path finding 2014-11-19 12:38:55 -05:00
Heng Li 8422950472 Merge branch 'dev' 2014-11-19 12:33:18 -05:00
Heng Li d36083bdc5 minor changes 2014-11-19 12:33:06 -05:00
Heng Li 84024101fa minor fix to a link 2014-11-19 12:31:32 -05:00
Heng Li 7e29a01b77 Merge branch 'dev' 2014-11-19 12:30:03 -05:00
Heng Li 1993cb634d Split README-alt.md into two documentations 2014-11-19 12:29:35 -05:00
Heng Li 9ade171f7a transfer read groups from the input BAM 2014-11-19 11:43:59 -05:00
Heng Li b5f6ed3020 r1005: insert arbitrary header lines 2014-11-19 10:59:05 -05:00
Heng Li 15c93e7a52 renamed extras to bwakit for clarity 2014-11-19 10:37:03 -05:00
Heng Li b31992991a Merge branch 'dev' 2014-11-19 09:37:10 -05:00
Heng Li bb7a97f68c update about bwa.kit 2014-11-19 09:36:56 -05:00
Heng Li 82ef0500e6 Merge branch 'dev' 2014-11-18 23:29:11 -05:00
Heng Li 56f1056b49 don't type empty files
This causes errors.
2014-11-18 23:28:46 -05:00
Heng Li 61ab329639 fine tune the wrapper scripts 2014-11-18 15:40:58 -05:00
Heng Li 80e4ecfa79 r998: smart pairing; allow mixture of SE/PE reads 2014-11-18 14:30:22 -05:00
Heng Li 6f9bf9a4ae minor change 2014-11-17 15:23:38 -05:00
Heng Li eb664c2fe8 added an evaluation section 2014-11-17 14:54:24 -05:00
Heng Li cee8149b12 Updated README for ALT mapping 2014-11-17 13:20:23 -05:00
Heng Li ad9d12c04d Removed a comment on hs38 lacking EBV
as is pointed out by Martin Pollard
2014-11-17 11:08:07 -05:00
Heng Li bf053c779b polish 2014-11-17 10:54:16 -05:00
Heng Li 0071c4ab22 polish the run script 2014-11-17 10:44:54 -05:00
Heng Li 792be78a80 replace run-gen-hs38* with run-gen-ref 2014-11-16 00:46:02 -05:00
Heng Li 050482ef77 fine tune 2014-11-13 19:52:47 -05:00
Heng Li 65c637b036 smarter prefix finder 2014-11-13 16:16:21 -05:00
Heng Li 4373a077d5 wrapper for bwa-mem 2014-11-13 15:51:00 -05:00
Heng Li a5c144db4d added scripts to generate hs38a.fa and hs38d6.fa 2014-11-13 12:53:29 -05:00
Heng Li fffe52a45b move bwa-typeHLA back to this repo 2014-11-13 12:50:56 -05:00
Heng Li 904afefbc6 r985: fix bug due to the lack of _pri contigs d6 2014-11-13 12:12:41 -05:00
Heng Li c5fe18438a r984: updated to the latest kseq.h 2014-11-13 11:12:23 -05:00
Heng Li 7eabcf42c4 r983: bugfix - wrong mate info
Picard now gives a clean bill.
2014-11-10 13:15:11 -05:00
Heng Li a81603217e mate chr is sometimes wrong 2014-11-10 10:16:53 -05:00
Heng Li b2b42cea7e removed contig weight & code cleanup
Contig weight was calculated based on a false assumption. It is actually not useful.
2014-11-07 12:45:01 -05:00
Heng Li 4e97cdfde8 move to a new project bwa-typeHLA
The two scripts cannot be used standalone anyway.
2014-11-06 09:13:15 -05:00
Heng Li c2f2cb03ce to be moved to a separate project 2014-11-06 09:12:53 -05:00
Heng Li 1bee29ef44 map to individual HLA ALT for meaningful mapQ 2014-11-06 00:37:59 -05:00
Heng Li 10de1e0b74 optionally output debegging info 2014-11-05 13:20:33 -05:00
Heng Li 0eee4fa1b0 nothing, really 2014-11-04 16:00:25 -05:00
Heng Li 2a41772d0a more command line help 2014-11-04 15:41:18 -05:00
Heng Li e5d7f4fc30 change the default max_len 2014-11-04 15:31:33 -05:00
Heng Li ccf03ffd22 control min-match-length
we still need this to kill false mapping/alignment
2014-11-04 15:26:10 -05:00