Commit Graph

1001 Commits (main)

Author SHA1 Message Date
Heng Li 9f84384ed2 reordering BWA-SW command-line prompt 2011-11-23 23:36:08 -05:00
Heng Li b17b6577ac removed a useless bwa-sw CMD option 2011-11-23 23:30:14 -05:00
Heng Li 107a9870ef incorrect mate pos in BWA-SW SE mode 2011-11-23 23:18:51 -05:00
Heng Li dec584d50b fixed a long-existing bug in trimming 2011-11-23 23:11:50 -05:00
Heng Li 84aa3fa696 useless script 2011-11-19 21:48:54 -05:00
Heng Li 182cb2e89c use standard SW when no SSE2 2011-11-19 19:38:21 -05:00
Heng Li dc4008936c avoid duplicated XA tags 2011-11-19 14:52:47 -05:00
Heng Li 8f89f55484 fixed a segfault when there are too few good bases. 2011-11-17 22:13:38 -05:00
Heng Li c8edcafb44 added SEAL 2011-11-12 20:48:35 -05:00
Heng Li 162f220deb updated README 2011-11-12 20:26:52 -05:00
Heng Li 9f2c77880d remove a useless file 2011-11-12 20:06:37 -05:00
Heng Li 770a5f2ae0 Release BWA-0.6.0 2011-11-12 20:04:39 -05:00
Heng Li f1517b845c updated manual 2011-11-12 18:35:04 -05:00
Heng Li 7544aca718 updated revision number 2011-11-12 16:56:21 -05:00
Heng Li 2f3cdcd55b bugfix: bwa-short MT does not work (by Peter) 2011-11-12 16:54:38 -05:00
Heng Li 56a18659b6 crash under non-typical setting (by John Marshall) 2011-11-12 16:53:53 -05:00
Heng Li 8060693411 multithreading works again 2011-11-12 16:50:58 -05:00
Heng Li fa8cfe5567 bugfix: wrong mapping quality 2011-11-12 12:12:45 -05:00
Heng Li b42910ada6 proper mate information 2011-11-12 00:49:21 -05:00
Heng Li e06685db45 bwa-sw PE seems working (SAM is incorrect) 2011-11-07 00:51:43 -05:00
Heng Li c8c79ef024 mate rescue seems working (not MT) 2011-11-06 16:20:40 -05:00
Heng Li 17eaac5a21 compute insert size distribution 2011-11-05 23:17:52 -04:00
Heng Li a29b179045 further preparation for pairing 2011-11-05 14:31:30 -04:00
Heng Li 06687a33b9 bwasw: read and align two fastq at a time 2011-11-05 14:00:01 -04:00
Heng Li a26096dd75 pair two single-end SAMs 2011-11-05 10:56:25 -04:00
Heng Li 4083fe9413 fixed a typo 2011-11-02 09:03:05 -04:00
Heng Li 673ae4aaf8 throw an error if insufficient memory during index 2011-10-31 13:26:24 -04:00
Heng Li 02946df28a fixed a off-by-1 bug 2011-10-27 13:55:48 -04:00
Heng Li 7babb54e4c drop smem based mapping algorithm
While we can compute smems very efficiently, there is still a long way to get
the alignment. On simulated data, this smem-based algorithm is 4X faster than
bwasw and twice as fast as bowtie2, but the accuracy is far lower than bwasw
and even lower than bowtie2 in the high-mapQ range. I am kind of sure that if
we continue to increase the mapping accuracy, the speed will approach to bwasw,
if not slower.

Smem-based mapping algorithm is still interesting, but given that I am short of
time, I will not explore it further.
2011-10-27 10:56:09 -04:00
Heng Li 7467671c30 minor change 2011-10-25 21:39:38 -04:00
Heng Li e890b8ac2e preliminary code to generate fake sam 2011-10-25 19:45:55 -04:00
Heng Li 55059443bd print msg to stderr; output more in fastmap 2011-10-25 15:06:13 -04:00
Heng Li 7664795ffb fixed a minor issue about +/-1 2011-10-25 13:00:41 -04:00
Heng Li 7168f5c10a updated revision number 2011-10-25 12:50:19 -04:00
Heng Li 4813257d4f remove debugging code 2011-10-25 12:38:33 -04:00
Heng Li f56edd07dd forward-backward search seems working 2011-10-25 12:31:36 -04:00
Heng Li aabb807734 concatenate for-rev sequences in the end 2011-10-25 11:22:08 -04:00
Heng Li ca809a44d9 build .pac in memory; prepare for further changes 2011-10-25 10:27:13 -04:00
Heng Li 7626595e3a backup the current debugging code; more changes 2011-10-25 10:03:57 -04:00
Heng Li 22c2252e15 added bidirectional bwt; seems buggy 2011-10-25 00:22:28 -04:00
Heng Li 7b4266a6e5 bugfix: integer overflow and strand error in sampe 2011-10-24 17:07:12 -04:00
Heng Li b59fd2bf47 fixed an integer overflow 2011-10-24 14:39:57 -04:00
Heng Li 8f3c780552 fixed a potential int overflow 2011-10-24 14:22:39 -04:00
Heng Li 1f970b4557 updated revision number 2011-10-24 14:14:42 -04:00
Heng Li eed46e802a fixed a bug about reverse alignment 2011-10-24 14:09:05 -04:00
Heng Li b204437c7e fixed negative mapping quality; still byggy 2011-10-24 14:00:36 -04:00
Heng Li 8512b55ce3 bwasw works on a couple of sequences 2011-10-24 13:42:32 -04:00
Heng Li 4c43c5914d this is better; but still buggy 2011-10-24 11:50:11 -04:00
Heng Li 29c3acfb31 not segfault immediately; but buggy 2011-10-24 09:36:52 -04:00
Heng Li b3397a1f14 changes to bwa-sw for the 64-bit support; unfinish 2011-10-21 13:32:45 -04:00