Released bwa-0.7.4-r385
This commit is contained in:
parent
2f6897c72b
commit
c14aaad1ce
37
bwa.1
37
bwa.1
|
|
@ -1,4 +1,4 @@
|
||||||
.TH bwa 1 "15 March 2013" "bwa-0.7.4" "Bioinformatics tools"
|
.TH bwa 1 "23 April 2013" "bwa-0.7.4" "Bioinformatics tools"
|
||||||
.SH NAME
|
.SH NAME
|
||||||
.PP
|
.PP
|
||||||
bwa - Burrows-Wheeler Alignment Tool
|
bwa - Burrows-Wheeler Alignment Tool
|
||||||
|
|
@ -44,7 +44,12 @@ for the BWA-MEM algorithm.
|
||||||
.SH COMMANDS AND OPTIONS
|
.SH COMMANDS AND OPTIONS
|
||||||
.TP
|
.TP
|
||||||
.B index
|
.B index
|
||||||
bwa index [-p prefix] [-a algoType] <in.db.fasta>
|
.B bwa index
|
||||||
|
.RB [ -p
|
||||||
|
.IR prefix ]
|
||||||
|
.RB [ -a
|
||||||
|
.IR algoType ]
|
||||||
|
.I db.fa
|
||||||
|
|
||||||
Index database sequences in the FASTA format.
|
Index database sequences in the FASTA format.
|
||||||
|
|
||||||
|
|
@ -55,20 +60,16 @@ Index database sequences in the FASTA format.
|
||||||
Prefix of the output database [same as db filename]
|
Prefix of the output database [same as db filename]
|
||||||
.TP
|
.TP
|
||||||
.BI -a \ STR
|
.BI -a \ STR
|
||||||
Algorithm for constructing BWT index. Available options are:
|
Algorithm for constructing BWT index. BWA implements two algorithms for BWT
|
||||||
.RS
|
construction:
|
||||||
.TP
|
|
||||||
.B is
|
.B is
|
||||||
IS linear-time algorithm for constructing suffix array. It requires
|
and
|
||||||
5.37N memory where N is the size of the database. IS is moderately fast,
|
.BR bwtsw .
|
||||||
but does not work with database larger than 2GB. IS is the default
|
The first algorithm is a little faster for small database but requires large
|
||||||
algorithm due to its simplicity. The current codes for IS algorithm are
|
RAM and does not work for databases with total length longer than 2GB. The
|
||||||
reimplemented by Yuta Mori.
|
second algorithm is adapted from the BWT-SW source code. It in theory works
|
||||||
.TP
|
with database with trillions of bases. When this option is not specified, the
|
||||||
.B bwtsw
|
appropriate algorithm will be chosen automatically.
|
||||||
Algorithm implemented in BWT-SW. This method works with the whole human
|
|
||||||
genome.
|
|
||||||
.RE
|
|
||||||
.RE
|
.RE
|
||||||
|
|
||||||
.TP
|
.TP
|
||||||
|
|
@ -220,10 +221,12 @@ deducted. [5]
|
||||||
Penalty for an unpaired read pair. BWA-MEM scores an unpaired read pair as
|
Penalty for an unpaired read pair. BWA-MEM scores an unpaired read pair as
|
||||||
.RI scoreRead1+scoreRead2- INT
|
.RI scoreRead1+scoreRead2- INT
|
||||||
and scores a paired as scoreRead1+scoreRead2-insertPenalty. It compares these
|
and scores a paired as scoreRead1+scoreRead2-insertPenalty. It compares these
|
||||||
two scores to determine whether we should force pairing. [17]
|
two scores to determine whether we should force pairing. A larger value leads to
|
||||||
|
more aggressive read pair. [17]
|
||||||
.TP
|
.TP
|
||||||
.B -p
|
.B -p
|
||||||
Assume the first input query file is interleaved paired-end FASTA/Q. See the command description for details.
|
Assume the first input query file is interleaved paired-end FASTA/Q. See the
|
||||||
|
command description for details.
|
||||||
.TP
|
.TP
|
||||||
.BI -R \ STR
|
.BI -R \ STR
|
||||||
Complete read group header line. '\\t' can be used in
|
Complete read group header line. '\\t' can be used in
|
||||||
|
|
|
||||||
Loading…
Reference in New Issue