Release BWA-0.7.3-r366
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NEWS
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NEWS
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Release 0.7.3 (15 March, 2013)
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~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
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Changes to BWA-MEM:
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* Bugfix: pairing score is inaccurate when option -A does not take the default
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value. This is a very minor issue even if it happens.
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* Bugfix: occasionally wrong CIGAR. This happens when in the alignment there
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is a 1bp deletion and a 1bp insertion which are close to the end of the
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reads, and there are no other substitutions or indels. BWA-MEM would not do
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a gapped alignment due to the bug.
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* New feature: output other non-overlapping alignments in the XP tag such that
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we can see the entire picture of alignment from one SAM line. XP gives the
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position, CIGAR, NM and mapQ of each aligned subsequence of the query.
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BWA-MEM has been used to align ~300Gbp 100-700bp SE/PE reads. SNP/indel calling
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has also been evaluated on part of these data. BWA-MEM generally gives better
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pre-filtered SNP calls than BWA. No significant issues have been observed since
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0.7.2, though minor improvements or bugs (e.g. the bug fixed in this release)
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are still possible. If you find potential issues, please send bug reports to
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<bio-bwa-help@lists.sourceforge.net> (free registration required).
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In addition, more detailed description of the BWA-MEM algorithm can be found at
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<https://github.com/lh3/mem-paper>.
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(0.7.3: 15 March 2013, r366)
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Release 0.7.2 (9 March, 2013)
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~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
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4
bwa.1
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bwa.1
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.TH bwa 1 "13 March 2013" "bwa-0.7.3" "Bioinformatics tools"
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.TH bwa 1 "15 March 2013" "bwa-0.7.3" "Bioinformatics tools"
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.SH NAME
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.PP
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bwa - Burrows-Wheeler Alignment Tool
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@ -580,7 +580,7 @@ XS Suboptimal alignment score
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XF Support from forward/reverse alignment
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XE Number of supporting seeds
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_
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XP Alt primary hits; format: /(chr,pos,CIGAR;mapQ,NM;)+/
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XP Alt primary hits; format: /(chr,pos,CIGAR,mapQ,NM;)+/
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.TE
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.PP
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