r455: release bwa-0.7.8
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NEWS
32
NEWS
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@ -1,3 +1,35 @@
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Release 0.7.8 (31 March, 2014)
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~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
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Changes in BWA-MEM:
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* Bugfix: off-diagonal X-dropoff (option -d) not working as intended.
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Short-read alignment is not affected.
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* Bugfix: unnecessarily large bandwidth used during global alignment,
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which reduces the mapping speed by ~5% for short reads. Results are not
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affected.
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* Bugfix: when the matching score is not one, paired-end mapping quality is
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inaccurate.
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* When the matching score (option -A) is changed, scale all score-related
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options accordingly unless overridden by users.
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* Allow to specify different gap open (or extension) penalties for deletions
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and insertions separately.
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* Allow to specify the insert size distribution.
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* Better and more detailed debugging information.
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With the default setting, 0.7.8 and 0.7.7 gave identical output on one million
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100bp read pairs.
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(0.7.8: 31 March 2014, r455)
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Release 0.7.7 (25 Feburary, 2014)
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Release 0.7.7 (25 Feburary, 2014)
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~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
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~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
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7
bwa.1
7
bwa.1
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@ -267,6 +267,13 @@ supported throughout BWA. Ideally, a value 0 for disabling all the output to
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stderr; 1 for outputting errors only; 2 for warnings and errors; 3 for
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stderr; 1 for outputting errors only; 2 for warnings and errors; 3 for
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all normal messages; 4 or higher for debugging. When this option takes value
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all normal messages; 4 or higher for debugging. When this option takes value
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4, the output is not SAM. [3]
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4, the output is not SAM. [3]
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.TP
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.BI -I \ FLOAT[,FLOAT[,INT[,INT]]]
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Specify the mean, standard deviation (10% of the mean if absent), max (4 sigma
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from the mean if absent) and min (4 sigma if absent) of the insert size
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distribution. Only applicable to the FR orientation. By default, BWA-MEM infers
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these numbers and the pair orientations given enough reads. [inferred]
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.RE
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.RE
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.TP
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.TP
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@ -132,8 +132,8 @@ int main_mem(int argc, char *argv[])
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fprintf(stderr, " -C append FASTA/FASTQ comment to SAM output\n");
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fprintf(stderr, " -C append FASTA/FASTQ comment to SAM output\n");
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fprintf(stderr, " -M mark shorter split hits as secondary\n\n");
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fprintf(stderr, " -M mark shorter split hits as secondary\n\n");
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fprintf(stderr, " -I FLOAT[,FLOAT[,INT[,INT]]]\n");
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fprintf(stderr, " -I FLOAT[,FLOAT[,INT[,INT]]]\n");
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fprintf(stderr, " specify the mean, standard deviation (10%% of mean if absent), max (4\n");
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fprintf(stderr, " specify the mean, standard deviation (10%% of the mean if absent), max\n");
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fprintf(stderr, " sigma from the mean if absent) and min of the insert size distribution.\n");
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fprintf(stderr, " (4 sigma from the mean if absent) and min of the insert size distribution.\n");
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fprintf(stderr, " FR orientation only. [inferred]\n");
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fprintf(stderr, " FR orientation only. [inferred]\n");
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fprintf(stderr, "\nNote: Please read the man page for detailed description of the command line and options.\n");
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fprintf(stderr, "\nNote: Please read the man page for detailed description of the command line and options.\n");
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fprintf(stderr, "\n");
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fprintf(stderr, "\n");
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