Heng Li
acfe7613db
dev-457: separated interval collection and seeding
2014-04-03 15:10:50 -04:00
Heng Li
3efb7c0e91
r455: release bwa-0.7.8
2014-03-31 15:27:23 -04:00
Heng Li
127c00cc96
dev-454: wording change in command line prompt
2014-03-31 12:03:27 -04:00
Heng Li
b27bdf1ae0
dev-453: change of -A scales -TdBOELU
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These paramemters are all proportional to -A.
2014-03-31 11:52:52 -04:00
Heng Li
b7076d9023
dev-r452: allow to specify insert size at cmd
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This is also very useful for debugging.
2014-03-31 11:21:03 -04:00
Heng Li
417c6d66c7
dev-r451: fixed a few bugs when -A!=1
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Something is still wrong.
2014-03-31 10:52:45 -04:00
Heng Li
9ce50a4e5e
dev-450: support diff ins/del penalties. NO TEST!!
2014-03-28 14:54:06 -04:00
Heng Li
578bb55c38
dev-449: unequal ins/del in global() and extend()
2014-03-28 14:15:38 -04:00
Heng Li
0c783399e8
dev-448: different ins/del penalties
2014-03-28 10:54:23 -04:00
Heng Li
2e9463ebf1
dev-r442: suppress exact full-length matches
2014-02-26 22:04:19 -05:00
Heng Li
1c19bc630f
Released bwa-0.7.7-r441
2014-02-25 01:05:37 -05:00
Heng Li
e879817373
r440: a condition not work due to a typo
2014-02-20 13:06:40 -05:00
Heng Li
ce026a07fc
r439: expose mem_opt_t::max_matesw
2014-02-19 13:10:33 -05:00
Heng Li
17fb85a227
r438: still an issue in MD
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It occurs when the global alignment disagrees with the local alignment.
2014-02-19 11:31:54 -05:00
Heng Li
52391a9855
r437: print timing for each batch of reads
2014-02-19 10:54:26 -05:00
Heng Li
bdd14d2946
r436: fix rare MD/NM-CIGAR inconsistencies
2014-02-19 10:08:43 -05:00
Heng Li
4adc34eccb
r435: bugfix - base not complemented on the rev
2014-02-18 10:32:24 -05:00
Heng Li
14aa43cca0
r434: added the missing bwasw/aln commands!
2014-02-12 15:39:02 -05:00
Heng Li
7c50bad567
Release bwa-0.7.6a-r433
2014-01-31 12:58:21 -05:00
Heng Li
5fdab3ae13
Released bwa-0.7.6-r432
2014-01-31 11:12:59 -05:00
Heng Li
f524c7d3d8
r431: added the MD tag to bwa-mem
2014-01-29 12:05:11 -05:00
Heng Li
ea3dc2f003
r430: fix a bug producing incorrect alignment
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Ksw uses two rounds of SSE2-SW to find the boundaries of an alignment. If the
second round gives a different score from the first round, it will fail. The
fix checks if this happens, though I have not dig into an example to understand
why this may happen in the first place.
2014-01-29 10:51:02 -05:00
Bradford Powell
c26ba4e376
fix duplicate PG lines in bwape and bwase
2014-01-05 14:54:48 -05:00
Heng Li
10cb6b0507
r428: allow to change the default chain_drop_ratio
2013-12-30 16:18:45 -05:00
Heng Li
f70d80a5a2
r427: fixed bugs in backtrack
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See comments in ksw_global() for details.
2013-12-30 15:40:18 -05:00
Heng Li
8b6ec74907
r424: fixed a bw bug in samse/pe
2013-11-25 15:48:04 -05:00
Heng Li
4219e58623
r423: bugfix - SE hits not random
2013-11-23 09:36:26 -05:00
Heng Li
29aa855432
r422: matesw hits not sorted
2013-11-21 14:43:50 -05:00
Heng Li
ff4762f3c7
r421: bw doubling in the final alignment
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In some cases, the band width used in the final alignment needs to be larger
than the band width in extension.
2013-11-20 10:04:16 -05:00
Heng Li
6e3fa0515a
r420: inferred bandwidth is not used in the final
2013-11-20 09:50:46 -05:00
Heng Li
ff6faf811a
r419: print the @PG line
2013-11-19 11:08:45 -05:00
Heng Li
deb19593aa
r418: use the new mapQ estimator by default
2013-11-02 12:25:53 -04:00
Heng Li
c564653b40
r416: removed a line of debugging code
2013-09-12 10:41:43 -04:00
Heng Li
7144a0cefc
r415: bug in the new (optional) mapQ computation
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I may use the new method as the default. Testing needed.
2013-09-09 17:51:05 -04:00
Heng Li
ebb7b02e9b
r414: fixed a bug caused by the last commit
2013-09-09 16:57:55 -04:00
Heng Li
b51a66e4c1
r413: fixed an issue causing redundant alignment
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I have seen a fosmid aligned to the same position but with two slightly
different CIGARs: 30000M and 29900M50D100M, possibly caused by tandem repeats.
0.7.5a will regard them as two distinct alignments and generates a very small
mapping quality. However, these two are essentially the same. Although there is
ambiguity in aligning the end of the fosmid, we should not penalize the entire
alignment with a small mapQ. This commit fixes this issue. More testing is
needed, though.
2013-09-09 11:36:50 -04:00
Heng Li
1346f03ff1
use the old mapQ by default
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the new mapQ overestimate
2013-09-06 14:04:41 -04:00
Heng Li
ed78df9184
Merge branch 'master' into clip2
2013-08-28 16:00:34 -04:00
Heng Li
3b84c03c1e
r406: allow to use diff clipping penalties
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for 5'-end or for 3'-end
2013-08-28 15:59:05 -04:00
John Marshall
b88718d8f4
Reformat note for 80 columns, and fix typo
2013-06-14 14:03:08 +01:00
Heng Li
7ec8b5c9e7
Release bwa-0.7.5a
2013-05-30 16:20:16 -04:00
Heng Li
ef18cb91cb
Release bwa-0.7.5-r404
2013-05-29 11:49:08 -04:00
Heng Li
73619754f8
r401: bugfix - forgot to change sampe
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some changes to samse should also be applied to sampe
2013-05-27 22:24:35 -04:00
Heng Li
599e840779
r397: multi changes/bugfixes to bwa-backtrack
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1. Check .sai versioning
2. Keep track of #ins and #del during backtrack
3. Use info above to get accurate aligned regions; don't call SW extension any more
4. Identify alignment crossing the for-rev boundary
5. Fixed a bug in printing the XA tag: ungapped alignments missing
2013-05-24 16:28:18 -04:00
Heng Li
bde5005f39
r396: er... the new tag is named SA not SP
2013-05-23 12:48:18 -04:00
Heng Li
3d2450ed97
r395: bugfix - hard clipping not applied on revaln
2013-05-23 12:45:14 -04:00
Heng Li
9441bb7f2a
r394: added future plan
2013-05-22 20:02:53 -04:00
Heng Li
9a6abe51b6
r391: better method to resolve xref alignment
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The old method does not work when the alignment bridges three chr. This may
actually happen often. The new method does not work all the time, either, but
should be better than the old one. It is also simpler, arguably.
2013-05-22 18:57:51 -04:00
Rob Davies
e88529687f
Merge branch 'master' into master_fixes. Merged up to r389.
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Conflicts:
bwamem.c
kopen.c
2013-04-29 12:09:30 +01:00
Heng Li
1a2bd2cf91
r389: return non-zero upon errors
2013-04-27 10:08:01 -04:00